Accurate Results in the Clinical Laboratory: A Guide to Error Detection and Correction, Second Edition, provides a comprehensive review of the factors leading to errors in all areas of clinical laboratory testing. This trusted guide addresses interference issues in all laboratory tests, including patient epigenetics, processes of specimen collection, enzymes and biomarkers. Clinicians and laboratory scientists will both benefit from this reference that applies discussions to both accurate specimen analysis and optimal patient care. Hence, this is the perfect reference for clinical laboratorians, from trainees, to experienced pathologists and directors.

• Provides comprehensive coverage across endocrine, oncology, hematology, immunohistochemistry, immunology, serology, microbiology, and molecular testing
• Includes new case studies that highlight clinical relevance and errors to avoid
• Highlights the best titles published within a variety of medical specialties
• Reviewed by medical librarians and content specialists, with key selections compiled in their annual list

Pathologists, clinical chemists, and toxicologists; practicing clinicians, fellows and residents in pathology, internal medicine, emergency medicine and family practice

Section I: Sources of errors in clinical laboratories: An overview
1. Variation, errors, and quality in the clinical laboratory
2. Errors in patient preparation, specimen collection, anticoagulant and preservative use: how to avoid such pre-analytical errors
3. Sample processing and specimen misidentification issues: major sources of pre-analytical errors
4. Effect of patient-related factors on clinical laboratory test results
5. Interferences of hemolysis, lipemia and high bilirubin on laboratory tests
6. Immunoassay design
7. Overview of other sources of interferences in immunoassays: prozone effect and interferences from heterophilic antibodies and autoantibodies
8. Biotin interference in clinical laboratory tests: sporadic problem or a serious clinical issue?

Section II: Sources of errors in clinical chemistry laboratory
9. Challenges in routine clinical chemistry testing analysis of small molecules
10. Challenges in routine clinical chemistry analysis: proteins and enzymes
11. Challenges in endocrinology testing
12. Pitfalls in testing for common tumor markers View more >