The first edition of The Paris System for Reporting Urinary Cytology introduced a completely new paradigm for detecting bladder cancer by urine cytology. This system concentrated on defining morphological characteristics of the most clinically significant form of bladder cancer, High Grade Urothelial Carcinoma. This new approach has been widely accepted throughout the world, and has become part of the daily practice of cytology. Considering that the first edition of The Paris System (TPS) introduced a new model of urinary cytodiagnosis, verification and expansion of initial material and data were anticipated. Based on evolving knowledge and readership requests, the group of highly experienced authors have created a new edition of TPS. This second edition includes areas and issues not originally covered. A new chapter on urine cytology of the upper tract, a rarely addressed topic, has been introduced. Furthermore, the issue of cellular degeneration is discussed in the criteria of all diagnostic categories. Examples of standardized reports are included in each chapter. Most importantly, a separate chapter presents data defining the risk of malignancy (ROM) for each diagnostic category to inform clinical management. New high quality images augment those of the first edition to better illustrate diagnostic clues and potential pitfalls. In addition to chapters on diagnostic criteria, current concepts of pathogenesis of bladder cancer, specimen adequacy and preparation, and ancillary tests are covered in separate chapters. A bonus to the volume is a comprehensive history of urine as the earliest diagnostic sample of human disease, richly illustrated with artworks from major museums.

Written by internationally recognized authorities, this comprehensive and evidence-based guide to urine cytology is supported by the newest data confirming the original concept and significance of diagnostic criteria defining High Grade Urothelial Carcinoma.TPS is an essential tool for anyone who is practicing urinary cytology, including cytotechnologists, pathologists-in-training and practicing pathologists. This book should find a place in every cytology laboratory throughout the world.

The Concept has been endorsed by the American Society of Cytopathology, and the International Academy of Cytology.

Eva M. Wojcik, M.D.

Chair of Pathology and Laboratory Medicine

Helen M. and Raymond M. Galvin Professor of Pathology & Urology

Regional Laboratory Medical Director, Loyola Medicine

Loyola University Medical Center

Department of Pathology and Laboratory Medicine

Maywood IL, USA

Daniel F. I. Kurtycz MD

Emeritus Professor,

Department of Pathology and Laboratory Medicine

University of Wisconsin School of Medicine and Public Health

Emeritus Medical Director,

Wisconsin State Laboratory of Hygiene

Madison, Wisconsin, USA,

Dorothy L. Rosenthal, MD

Professor Emerita of Pathology/Cytopathology

The Johns Hopkins School of Medicine

Baltimore MD, USA